Science behind metis Anti-Age 02

The science behind metis Anti-Age 02

Effective supplements?
Brought to you ecologically!

We strongly question today's supplements. Skeptical we certainly are. A high concentrationfor less wrinkles? Check. Each formula has been perfected to maximize the effect of the various ingredients. Thus, each capsule contains a decisive dose of natural, active substances.

metis Anti-Age 02 helps you fight the first signs of skin aging. It hydrates the skin and stimulates the internal production of collagen. Go for a healthy and radiant skin and fight your wrinkles from within!

Sugar free
No artificial colors
No synthetic preservatives
No artificial flavors or fragrances
Not addictive

Dracobelle®, Marine collagen & hyaluronic acid

  • Marine collagen types 1 and 3 are the most effective forms of collagen and help maintain normal skin firmness, elasticity and structure.
  • Low molecular hyaluronic acid is the best orally absorbable form that ensures the skin stays hydrated and also corrects fine wrinkles and lines.
  • Dracobelle® provides clinically proven improvement in skin moisture, elasticity and density, as well as increased collagen density.

Keratin (cynatine®), olive leaf extract & co-factors

  • Cyatine® is a bio-absorbable form of keratin, the building material for healthy hair, skin and nails.
  • Olive Leaf Extract is one of the strongest antioxidants on the market, protecting your body from oxidation and oxidative stress. So this protects your skin, hair and nails from harmful elements from outside.
  • Co-factors: Vitamin B2, B3, C, Biotin and Copper. All these elements are added to support the action of the main elements and give the skin its general nutrients.


Skin Test Institute, CH-2008 Neuchâtel: Food Supplement Ingredient Study for Beauty from within with DracoBelleTM Nu. Thisstudy was conducted October 2017 - December 2017 Sponsor: Mibelle AG Biochemistry, 5033 Buchs, Switzerland

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. (2020, November 3). PubMed Central (PMC).

Bear C, Wood S, Veghte RH. A clinical trial to investigate the effect of Cynatine HNS on hair and nail parameters. ScientificWorldJournal. 2014;2014:641723. doi: 10.1155/2014/641723. Epub 2014 Oct 16. PMID: 25386609; PMCID: PMC4214097.

"More in a capsule. More out of life."

Are you willing to give it your all? Then you will get more from us. Because in your hectic life, the bar is sometimes set high. How do you stay on top of your schedule? How do you start your day well-rested? metis offers you an effective dose of 'doing' and 'dreaming'. Replenish your nutrition and go full steam ahead.

Benefits and ingredients

We have carefully selected 10 natural ingredients, each with its own specific action and benefits. metis Anti-Age 02 has four main benefits:

Increases skin elasticity
 Hydrates the skin
Supports production of collagen
Helps maintain tight skin

Collagen type 1 and 3


Collagen is an important glue forming protein in our body. It provides strength. Our joints, bones, muscles, but also hair and nails are made of collagen. Collagen also ensures the firmness and elasticity of the skin. Collagen fibers in the epidermis, called the dermis, influence the skin structure and firmness from within. Collagen thus plays an important role in our entire body!


Important in the production of the body's own collagen is vitamin C, in addition the body needs a supply of amino acids such as glycine and proline. One of the food sources that is richest in these specific amino acids is collagen! By using collagen hydrolisate you provide your body with the right nutrients to repair and create skin, hair, nails, tendons and bones to strengthen and support.


Improved health of the skin:

Joint pain

Improved intestinal health

Hyaluronic Acid


Hyaluronic acid is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints.


Hyaluronic acid acts as a cushion and lubricant in the joints and other tissues. In addition, it can affect the way the body responds to injuries. Only our low molecular hyaluronic acid is well absorbed orally.


Provides better moisture absorption and prevents moisture loss, giving the skin a healthy, firm appearance.

Has antioxidant properties, protects against free radicals.

Effective in helping maintain skin elasticity.

Promotes wound healing

Keratin (cynatin®)


Cynatine HNS is a revolutionary cosmeceutical ingredient composed of dissolved keratin, a protein that occurs naturally in the body.


Cynatine HNS replenishes the body with bioavailable keratin that helps protect and repair damaged hair, nails and skin.


Cynatine reduces fine lines and wrinkles

Cynatine promotes skin firmness and elasticity

Cynatine reduces redness caused by inflammation or sensitive skin

Cynatine improves the luminosity and radiance of the skin

Moldovan melissa extract (Dracocephalum moldavica, Dracobelle™)


Moldovan melissa extract (Dracocephalum moldavica) is a member of the mint family and is traditionally used in Central Asia, for which antioxidant, cardio-protective and anti-aging effects have been reported.


Dracobelle mimics the effects of caloric restriction, a novel anti-aging mechanism mediated by activation of AMPK and FOXO, leading to improved cellular defenses, resistance to oxidative stress, cell detoxification and repair.


Improvement in skin moisture, elasticity and density, as well as for increased collagen density.

Olive leaf extract (20% oleuropein)


Olive leaf extract refers to the molecules that come from the leaves of the olive plant. The olive fruit (what we consume) is what olive oil is made from and olive leaf extract has several chemical compounds that alter physiology and neurochemistry.


The main bioactive molecules in olive leaf extract are oleuropein and hydroxytyrosol, which are known to affect blood pressure, lower cholesterol, and also have neuroprotective and neurogenic effects.


reduces cardiovascular risks, such as atherosclerosis

lowers blood pressure

eliminates free radicals

strengthens immunity

reduces inflammation

Vitamin B2


Riboflavin (vitamin B2) is needed for the body's energy supply. Riboflavin is found mainly in milk and milk products, but also in meat, meat products, vegetables, fruits, bread and grain products.


Riboflavin is involved in the metabolism of macronutrients and in the production of some other B-complex vitamins. It is known to participate in redox reactions in metabolic pathways through the riboflavin-derived cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) by acting as electron carriers.


Is good for your nervous system.

Promotes your energy metabolism.

Is important for healthy skin and mucous membranes.

Helps protect the cells in your body from oxidative damage.

Ensures the maintenance of good iron levels in your blood.

Helps with fatigue.

Vitamin B3


Vitamin B3, also known as niacin, is an essential nutrient best known for its normalization of cholesterol markers and cardiovascular interactions.


One of the main benefits of vitamin B3 to the brain is general cognition and longevity. Niacin supplementation is thought to increase specific nucleotides in our brain cells, which are associated with cognition and nerve growth.


Lowers LDL cholesterol

Increases HDL cholesterol

May aid in the prevention of heart disease

Improves brain function

Improves skin function

Vitamin C


Praised as the greatest gift for anyone with a common cold, vitamin C is an essential nutrient with antioxidant properties.


The enzymatic actions involved in vitamin C are numerous and very important for adequate cognitive function. In particular, vitamin C is an enzymatic cofactor for an enzyme called dopamine beta-hydroxylase, which helps optimize the production of important focus and concentration hormones such as dopamine, adrenaline, and norepinephrine.


Helps the body produce collagen, L-carnitine, and some neurotransmitters.

As an antioxidant, it helps remove unwanted substances, known as reactive oxidative species (ROS), from the body.

It helps the body absorb iron.

It stimulates the immune system.

It promotes wound healing.



Biotin is an essential nutrient, also known as vitamin B7, that is essential for numerous enzymatic processes in the brain and body. Although humans need biotin for everything from food metabolism to supporting neurological function, we cannot make our own biotin, making us dependent on food sources and gut bacteria.


Biotin acts as a coenzyme for multiple carboxylases in humans, and it alters the irreversible carboxylation of acetyl-CoA to malonyl-CoA.These enzymes are vital in numerous metabolic processes. The mechanism of action of biotin occurs by attaching to specific lysine residues.


Improves the health of the hair

Supports nail health

Breaks down macronutrients



Copper plays an important role in the maintenance and production of collagen and elastin. It has antioxidant properties so that cells remain strong and healthy. In addition, it combats free radicals, and their damage.


Copper is needed in the formation of connective tissue and bones. It also ensures the formation of pigment of the hair, proper functioning of the immune system and blood clotting. Copper is involved in the body in the transfer of oxygen (oxidation reactions).


Enhances the radiance of the skin.

Supports the normal pigmentation of the skin.

Discover metis Anti-

Age 02

Created by a pharmacist

Originally made for his children

Pharmacist Dirk Christiaen wanted to support his studying children with effective nutritional supplements during exams, but found nothing to please his expert eye.

So he set to work himself to create effective formulas whose effect you can really feel. Despite the very critical attitude of his children, it turned out not to miss its effect....

Discover the story behind Metis